Oxymetholone(Anadrol)CAS:434-07-1

Synonyms:

UNII-77LW93C64T;77LW93C64T;156197-08-9;434-07-1;17-Hydroxy-2-(hydroxymethylene)-17-methylandrostan-3-one, (2E,5alpha,17beta)-;Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (2E,5alpha,17beta)-;SMR000058877;Oxymetholone [USAN:BAN:INN:JAN];NSC 26198;MLS000759530;MLS001424048;CHEMBL4303342;(5-alpha,17-beta)-17-Hydroxy-2-(hydroxymethylene)-17-methylandrostan-3-one;Androstan-3-ona, 17-hidroxi-2-(hidroximetileno)-17-metil-, (5alfa,17beta )-;Androstan-3-one, 17-hydroxy-2-(hydroxymethylene)-17-methyl-, (5.alpha.,17.beta.)-;HMS2051H15;HMS3715N20;AKOS015962213;CCG-100962;CCG-221269;NC00212;AC-16143;Q27266591;(2E,5alpha,17beta)-17-hydroxy-2-(hydroxymethylene)-17-methylandrostan-3-one;17-HYDROXY-2-(HYDROXYMETHYLENE)-17-METHYLANDROSTAN-3-ONE, (2E,5.ALPHA.,17.BETA.)-;ANDROSTAN-3-ONE, 17-HYDROXY-2-(HYDROXYMETHYLENE)-17-METHYL-, (2E,5.ALPHA.,17.BETA.)-

Canonical SMILES:

CC12CCC3C(C1CCC2(C)O)CCC4C3(CC(=CO)C(=O)C4)C

Isomeric SMILES:

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(C/C(=C\O)/C(=O)C4)C

description

Oxymetholone is an orally active synthetic anabolic steroid and a 17alpha-methylated derivative of dihydrotestosterone, with androgenic activity. Although oxymetholone has low affinity for binding the androgen receptor (AR), it strongly activates AR-mediated signaling, which stimulates both protein synthesis and erythropoietin production. This agent may stimulate muscle growth, induce hemoglobin production and red blood cell formation, and promote increased bone density.

Description

Oxymetholone is a synthetic, orally active anabolic-androgenic steroid (AAS) and 17α-methylated derivative of dihydrotestosterone (DHT). It is mainly used for the treatment of osteroporosis and anemia (low red blood cell count). It can also stimulate the muscle growth in malnourished or underdeveloped patients. It also has the potential to treat the HIV wasting syndrome. Oxymetholone can also lead to an even buildup in strength, which is its secondary characteristics, making it an excellent steroid to be coupled with other anabolic steroids to yield synergetic effect.

Uses

Oxymetholone is used in treatment of myelofibrosis and myelosuppression. This drug can provoke bone marrow cells and rise the blood cells in the peripheral blood vessels. It has been approved by the US Food and Drug Administration for the treatment of anemia caused by deficient red cell production. It is effective in catabolic states, replacement of male sex steroids in men who have androgen deficiency, and in eugonadal male and female patients with acquired immunodeficiency syndrome-associated wasting.

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